FBI Uses Advanced Tech to Analyze DNA in Guthrie Case

Hair sample from Arizona home tested with advanced FBI technology
Posted Apr 17, 2026 1:00 AM CDT
FBI Uses Advanced Tech to Analyze DNA in Guthrie Case
FILE - An ever-growing collection of yellow flowers and notes sit at the home of Nancy Guthrie, the missing mother of "Today" show host Savannah Guthrie, on March 6, 2026, in Tucson, Ariz.   (AP Photo/Rebecca Noble, File)

Federal investigators are taking a fresh look at a piece of evidence in the disappearance of Nancy Guthrie, the 84-year-old mother of Today co-anchor Savannah Guthrie, who was abducted from her Tucson home on Feb. 1. A private lab working with the Pima County Sheriff's Department recently transferred a hair sample collected in February to the FBI, which is now using advanced forensic tools to try to pull usable DNA from it, according to law enforcement sources who spoke to ABC News.

An FBI official stressed the material is not newly discovered evidence but a previously known sample that took 11 weeks to be moved from the Florida lab to the FBI. Authorities have said the DNA from Guthrie's home appears to contain genetic material from more than one person, requiring lengthy analysis that could stretch another six months. According to Fox News, some experts believe there could be DNA from three people in some of the samples collected at the scene. Multiple labs nationwide are working the case, which still involves about two dozen investigators but has produced few public leads since early doorbell-camera footage and a surveillance image of a possible subject were released. Savannah Guthrie has spoken publicly about her mother's abduction, saying her family "cannot be at peace" until they get answers.

Meanwhile, USA Today reports there has been an increased police presence in Guthrie's neighborhood after complaints from others who live in the area. "The sheriff recently told residents in the Guthrie neighborhood during a meeting that there have been increased patrols in the area in response to complaints about streamers and citizen journalists possibly trespassing," the sheriff's department says.

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